Histone-lysine N-methyltransferase SUVR4 (SUVR4), Recombinant Protein
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Histone-lysine N-methyltransferase SUVR4 (SUVR4), Recombinant Protein

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Cat: RP05040
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Histone-lysine N-methyltransferase SUVR4 (SUVR4)
Product Gene Name
SUVR4 recombinant protein
Product Synonym Gene Name
SUVR4
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MISLSGLTSS VESDLDMQQA MLTNKDEKVL KALERTRQLD IPDEKTMPVL MKLLEEAGGN WSYIKLDNYT ALVDAIYSVE DENKQSEGSS NGNRGKNLKV IDSPATLKKT YETRSASSGS SIQVVQKQPQ LSNGDRKRKY KSRIADITKG SESVKIPLVD DVGSEAVPKF TYIPHNIVYQ SAYLHVSLAR ISDEDCCANC KGNCLSADFP CTCARETSGE YAYTKEGLLK EKFLDTCLKM KKEPDSFPKV YCKDCPLERD HDKGTYGKCD GHLIRKFIKE CWRKCGCDMQ CGNRVVQRGI RCQLQVYFTQ EGKGWGLRTL QDLPKGTFIC EYIGEILTNT ELYDRNVRSS SERHTYPVTL DADWGSEKDL KDEEALCLDA TICGNVARFI NHRCEDANMI DIPIEIETPD RHYYHIAFFT LRDVKAMDEL TWDYMIDFND KSHPVKAFRC CCGSESCRDR KIKGSQGKSI ERRKIVSAKK QQGSKEVSKK RK
Sequence Positions
1-492, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
55,855 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Histone-lysine N-methyltransferase

NCBI/Uniprot Data

NCBI Accession #
NP_187088.2
NCBI GI #
22330839
NCBI GenBank Nucleotide #
NM_111309.3
NCBI GeneID
819593
NCBI Official Full Name
SET-domain containing protein lysine methyltransferase family protein
NCBI Official Symbol
SUVR4
NCBI Official Synonym Symbols
SDG31; SET DOMAIN PROTEIN 31; T27C4.2; T27C4_2
NCBI Protein Information
SET-domain containing protein lysine methyltransferase family protein
NCBI Summary
Encodes SUVR4, a nucleolar histone methyltransferase with preference for monomethylated H3K9. One of the four closely related Arabidopsis SUVR proteins that belong to the SU(VAR)3-9 subgroup of SET-domain proteins. Proteins containing the evolutionarily conserved SET domain are involved in regulation of eukaryotic gene expression and chromatin structure through their histone lysine methyltransferase (HMTase) activity. SUVR1, SUVR2 and SUVR4 proteins contain a novel domain at their N-terminus, and a SUVR specific region preceding the SET domain.
UniProt Gene Name
SUVR4
UniProt Synonym Gene Names
SDG31; SET31; Su(var)3-9-related protein 4
UniProt Protein Name
Histone-lysine N-methyltransferase SUVR4
UniProt Synonym Protein Names
Protein SET DOMAIN GROUP 31; Suppressor of variegation 3-9-related protein 4; Su(var)3-9-related protein 4
UniProt Primary Accession #
Q8W595
UniProt Secondary Accession #
Q3EBC4; Q9M848
UniProt Related Accession #
Q8W595
UniProt Comments
Histone methyltransferase that converts monomethylated 'Lys-9' of histone H3 (H3K9me1) to dimethylated 'Lys-9' (H3K9me2) in the absence of bound ubiquitin, and to trimethylated 'Lys-9' (H3K9me3) in the presence of bound ubiquitin. Acts in a locus-specific manner and contributes to the transcriptional silencing of pseudogenes and transposons. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.

For research use only, not for clinical use.