NCBI Accession #
NP_180049.2
NCBI GenBank Nucleotide #
NM_128034.2
NCBI Official Full Name
SET domain group 21
NCBI Official Symbol
SDG21
NCBI Official Synonym Symbols
F27A10.5; F27A10_5; SET domain group 21; SU(VAR)3-9 HOMOLOG 8; SUVH8
NCBI Protein Information
SET domain group 21
NCBI Summary
Encodes a SU(VAR)3-9 homolog, a SET domain protein (Homology Subgroup V; Orthology Group 1). Known SET domain proteins are involved in epigenetic control of gene expression. There are 10 SUVH genes in Arabidopsis and members of this subfamily of the SET proteins have an additional conserved SRA domain. This protein is a putative histone methyltransferase (predicted to methylate H3K9/20) related to the the Drosophila Su(var)3-9 and mammalian G9a proteins.
UniProt Synonym Gene Names
SDG21; SET21; H3-K9-HMTase 8; Su(var)3-9 homolog protein 8
UniProt Protein Name
Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH8
UniProt Synonym Protein Names
Histone H3-K9 methyltransferase 8; H3-K9-HMTase 8; Protein SET DOMAIN GROUP 21; Suppressor of variegation 3-9 homolog protein 8; Su(var)3-9 homolog protein 8
UniProt Primary Accession #
Q9C5P0
UniProt Secondary Accession #
Q9TP24
UniProt Related Accession #
Q9C5P0
UniProt Comments
Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.