NCBI Accession #
NP_850030.1
NCBI GenBank Nucleotide #
NM_179699.3
NCBI Official Full Name
SU(VAR)3-9 homolog 6
NCBI Official Symbol
SUVH6
NCBI Official Synonym Symbols
SDG23; SET DOMAIN PROTEIN 23; SU(VAR)3-9 homolog 6; T9I22.18; T9I22_18
NCBI Protein Information
SU(VAR)3-9 homolog 6
NCBI Summary
Encodes a SU(VAR)3-9 homolog, a methyltransferase involved in histone methylation. The protein was shown to bind to methylated cytosines of CG, CNG and CNN motifs but has a preference for the latter two. This is a member of a subfamily of SET proteins that shares a conserved SRA domain.
UniProt Synonym Gene Names
SDG23; SET23; H3-K9-HMTase 6; Su(var)3-9 homolog protein 6
UniProt Protein Name
Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6
UniProt Synonym Protein Names
Histone H3-K9 methyltransferase 6; H3-K9-HMTase 6; Protein SET DOMAIN GROUP 23; Suppressor of variegation 3-9 homolog protein 6; Su(var)3-9 homolog protein 6
UniProt Primary Accession #
Q8VZ17
UniProt Secondary Accession #
Q9C5P2; Q9ZQ40
UniProt Related Accession #
Q8VZ17
UniProt Comments
Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression. Seems to act preferentially on dsMRNA.