NCBI Accession #
NP_001324386.1
NCBI GenBank Nucleotide #
NM_001336549.1
NCBI Official Full Name
SU(VAR)3-9 homolog 5
NCBI Official Symbol
SUVH5
NCBI Official Synonym Symbols
SET DOMAIN-CONTAINING PROTEIN 9; SGD9; SU(VAR)3-9 homolog 5; T4C15.17; T4C15_17
NCBI Protein Information
SU(VAR)3-9 homolog 5
NCBI Summary
Encodes SU(var)3-9 homologue 5 (SUVH5). SUVH5 has histone methyltransferase (MTase) activity in vitro and contributes to the maintenance of H3 mK9 (methylation of histone H3 at Lys-9) and CMT3-mediated non-CG methylation in vivo. This is a member of a subfamily of SET proteins that shares a conserved SRA domain.
UniProt Synonym Gene Names
SDG9; SET9; H3-K9-HMTase 5; Su(var)3-9 homolog protein 5
UniProt Protein Name
Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5
UniProt Synonym Protein Names
Histone H3-K9 methyltransferase 5; H3-K9-HMTase 5; Protein SET DOMAIN GROUP 9; Suppressor of variegation 3-9 homolog protein 5; Su(var)3-9 homolog protein 5
UniProt Primary Accession #
O82175
UniProt Related Accession #
O82175
UniProt Comments
Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.