Histone-lysine N-methyltransferase ATXR6 (ATXR6), Recombinant Protein
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Histone-lysine N-methyltransferase ATXR6 (ATXR6), Recombinant Protein

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Cat: RP04989
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Histone-lysine N-methyltransferase ATXR6 (ATXR6)
Product Gene Name
ATXR6 recombinant protein
Product Synonym Gene Name
ATXR6
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MVAVRRRRTQ ASNPRSEPPQ HMSDHDSDSD WDTVCEECSS GKQPAKLLLC DKCDKGFHLF CLRPILVSVP KGSWFCPSCS KHQIPKSFPL IQTKIIDFFR IKRSPDSSQI SSSSDSIGKK RKKTSLVMSK KKRRLLPYNP SNDPQRRLEQ MASLATALRA SNTKFSNELT YVSGKAPRSA NQAAFEKGGM QVLSKEGVET LALCKKMMDL GECPPLMVVF DPYEGFTVEA DRFIKDWTII TEYVGDVDYL SNREDDYDGD SMMTLLHASD PSQCLVICPD RRSNIARFIS GINNHSPEGR KKQNLKCVRF NINGEARVLL VANRDISKGE RLYYDYNGYE HEYPTEHFV
Sequence Positions
1-349, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
39,640 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Histone-lysine N-methyltransferase

NCBI/Uniprot Data

NCBI Accession #
NP_197821.1
NCBI GI #
15237940
NCBI GenBank Nucleotide #
NM_122341.3
NCBI GeneID
832503
NCBI Official Full Name
TRITHORAX-RELATED PROTEIN 6
NCBI Official Symbol
ATXR6
NCBI Official Synonym Symbols
ARABIDOPSIS TRITHORAX-RELATED PROTEIN 6; MOP9.7; MOP9_7; SDG34; SET DOMAIN PROTEIN 34
NCBI Protein Information
TRITHORAX-RELATED PROTEIN 6
NCBI Summary
Encodes a SET-domain protein, a H3K27 monomethyltransferases required for chromatin structure and gene silencing. Regulates heterochromatic DNA replication. Contains a PCNA-binding domain. ATXR6 accumulates preferentially during the late G1 or S phase, suggesting that it plays a role in cell-cycle regulation or progression.
UniProt Gene Name
ATXR6
UniProt Synonym Gene Names
SDG34; SET34; TRX-related protein 6
UniProt Protein Name
Histone-lysine N-methyltransferase ATXR6
UniProt Synonym Protein Names
Protein SET DOMAIN GROUP 34; Trithorax-related protein 6; TRX-related protein 6
UniProt Primary Accession #
Q9FNE9
UniProt Related Accession #
Q9FNE9
UniProt Comments
Histone methyltransferase that specifically monomethylates 'Lys-37' of histone H3 (H3K27me1). Has higher activity on nucleosomes containing H3.1 than H3.3. Involved in the formation of constitutive heterochromatin and the silencing of heterochromatic elements. May act as a positive regulator of the G1-S transition. Influences which sets of rRNA gene variants are expressed or silenced. Up-regulated by E2FB.

For research use only, not for clinical use.