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Histone-lysine N-methyltransferase ATX1 (ATX1), Recombinant Protein
Cat: RP02233
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Histone-lysine N-methyltransferase ATX1 (ATX1) , partial
Product Gene Name
ATX1 recombinant protein
Product Synonym Gene Name
ATX1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
54,058 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Histone-lysine N-methyltransferase
NCBI/Uniprot Data
NCBI Accession #
NP_850170.1
NCBI GI #
30685011
NCBI GenBank Nucleotide #
NM_179839.3
NCBI GeneID
817721
NCBI Official Full Name
homologue of trithorax
NCBI Official Symbol
ATX1
NCBI Official Synonym Symbols
homologue of trithorax; SDG27; SET DOMAIN PROTEIN 27; T9H9.17; T9H9_17
NCBI Protein Information
homologue of trithorax
NCBI Summary
Encodes a homolog of trithorax, a histone-lysine N-methyltransferase. Involved in trimethylating histone H3-lysine 4. Involved in the formation, placement, and identity of flower organs. Role in regulation of homeotic genes. Functions as a receptor of phosphatidylinositol 5-phosphate. Localizes to cytoplasm, plasma membrane and nuclei, shifting to nuclei in the presence of PI5P.
UniProt Gene Name
ATX1
UniProt Synonym Gene Names
TRX-homolog protein 1
UniProt Protein Name
Histone-lysine N-methyltransferase ATX1
UniProt Synonym Protein Names
Protein SET DOMAIN GROUP 27
UniProt Primary Accession #
Q9C5X4
UniProt Secondary Accession #
Q84WP4; Q9SIP3
UniProt Related Accession #
Q9C5X4
UniProt Comments
Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Required to maintain the active state of class A (AP1 and AP2), class B (PI and AP3) and class C (AG) floral homeotic genes at early stages of flower development. Regulates floral organ identity and flowering transition. Functions as a receptor for the lipid messenger phosphatidylinositol 5-phosphate (PI5P), which regulates negatively its transcriptional activation activity.
For research use only, not for clinical use.