Histone H3-like centromeric protein HTR12 (HTR12), Recombinant Protein
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Histone H3-like centromeric protein HTR12 (HTR12), Recombinant Protein

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Cat: RP05345
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Histone H3-like centromeric protein HTR12 (HTR12)
Product Gene Name
HTR12 recombinant protein
Product Synonym Gene Name
HTR12
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
ARTKHRVTRS QPRNQTDAAG ASSSQAAGPT TTPTRRGGEG GDNTQQTNPT TSPATGTRRG AKRSRQAMPR GSQKKSYRYR PGTVALKEIR HFQKQTNLLI PAASFIREVR SITHMLAPPQ INRWTAEALV ALQEAAEDYL VGLFSDSMLC AIHARRVTLM RKDFELARRL GGKGRPW
Sequence Positions
2-178, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
19,709 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Histone H3-like centromeric protein

NCBI/Uniprot Data

NCBI Accession #
NP_001030927.1
NCBI GI #
79316243
NCBI GenBank Nucleotide #
NM_001035850.3
NCBI GeneID
839104
NCBI Official Full Name
Histone superfamily protein
NCBI Official Symbol
HTR12
NCBI Official Synonym Symbols
CENH3; CENTROMERIC HISTONE H3; F6F3.17; F6F3_17
NCBI Protein Information
Histone superfamily protein
NCBI Summary
Encodes a centromere-identifying protein histone H3 variant. Localized at centromeres in both mitotic and meiotic cells.
UniProt Gene Name
HTR12
UniProt Synonym Gene Names
CENH3
UniProt Protein Name
Histone H3-like centromeric protein HTR12
UniProt Synonym Protein Names
Centromeric histone CENH3
UniProt Primary Accession #
Q8RVQ9
UniProt Secondary Accession #
Q8LCW8; Q9LNI6
UniProt Related Accession #
Q8RVQ9
UniProt Comments
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division .

For research use only, not for clinical use.