Histone deacetylase 19 (HDA19), Recombinant Protein
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Histone deacetylase 19 (HDA19), Recombinant Protein

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Cat: RP03955
Size: 0.05 mg (E-Coli)/ 0.05 mg (Baculovirus)/ 0.2 mg (E-Coli)/ 0.2 mg (Yeast)/ 0.5 mg (E-Coli)/ 0.05 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 0.5 mg (Yeast)/ 1 mg (E-Coli)/ 0.5 mg (Baculovirus)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Histone deacetylase 19 (HDA19) , partial
Product Gene Name
HDA19 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MDTGGNSLAS GPDGVKRKVC YFYDPEVGNY YYGQGHPMKP HRIRMTHALL AHYGLLQHMQ VLKPFPARDR DLCRFHADDY VSFLRSITPE TQQDQIRQLK RFNVGEDCPV FDGLYSFCQT YAGGSVGGSV KLNHGLCDIA INWAGGLHHA KKCEASGFCY VNDIVLAILE LLKQHERVLY VDIDIHHGDG VEEAFYATDR VMTVSFHKFG DYFPGTGHIQ DIGYGSGKYY SLNVPLDDGI DDESYHLLFK PIMGKVMEIF RPGAVVLQCG ADSLSGDRLG CFNLSIKGHA ECVKFMRSFN VPLLLLGGGG YTIRNVARCW CYETGVALGV EVEDKMPEHE YYEYFGPDYT LHVAPSNMEN KNSRQMLEEI RNDLLHNLSK LQHAPSVPFQ ERPPDTETPE VDEDQEDGDK RWDPDSDMDV DDDRKPIPSR VKREAVEPDT KDKDGLKGIM ERGKGCEVEV DESGSTKVTG VNPVGVEEAS VKMEEEGTNK GGAEQAFPPK T
Sequence Positions
1-501aa, full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
56,023 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Histone deacetylase

NCBI/Uniprot Data

NCBI Accession #
NP_195526.1
NCBI GI #
15233694
NCBI GenBank Nucleotide #
NM_119974.4
NCBI GeneID
829969
NCBI Official Full Name
histone deacetylase 1
NCBI Official Symbol
HD1
NCBI Official Synonym Symbols
ARABIDOPSIS HISTONE DEACETYLASE 1; ARABIDOPSIS HISTONE DEACETYLASE 19; ATHD1; ATHDA19; ATRPD3A; F20D10.250; F20D10_250; HDA1; HDA19; HISTONE DEACETYLASE; histone deacetylase 1; HISTONE DEACETYLASE 19; HISTONE DEACETYLASE19; RPD3A
NCBI Protein Information
histone deacetylase 1
NCBI Summary
Encodes a histone deacetylase that enhances AtERF7-mediated transcriptional repression. Binds SIM3 and ERF7. Expressed in the nucleus in most tissues examined and throughout the life of the plant. Involved in jasmonic acid and ethylene dependent pathogen resistance. The sequence in GenBank has 17 AG dinucleotide repeats missing, which is also missing in Ler shotgun sequence from Cereon. Although it is annotated to be in Columbia, the GB sequence is probably not of Columbia origin. Plays a role in embryogenesis as mutants grown at higher temperatures display abnormalities in the organization of the root and shoot. Plant lines expressing an RNAi construct targeted against HDA19 shows some resistance to agrobacterium-mediated root transformation.
UniProt Gene Name
HDA19
UniProt Synonym Gene Names
HD
UniProt Protein Name
Histone deacetylase 19
UniProt Primary Accession #
O22446
UniProt Secondary Accession #
Q0WWG3; Q9SZL3
UniProt Related Accession #
O22446
UniProt Comments
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDA19 is involved in jasmonic acid and ethylene signaling of pathogen response. Part of a repressor complex including APETALA2 (AP2) and TOPLESS (TPL) that control the expression domains of numerous floral organ identity genes (PubMed:23034631).

For research use only, not for clinical use.