NCBI Accession #
NP_200915.2
NCBI GenBank Nucleotide #
NM_125500.3
NCBI Official Full Name
histone deacetylase of the RPD3/HDA1 superfamily 18
NCBI Official Symbol
HDA18
NCBI Official Synonym Symbols
A. THALIANA HISTONE DEACETYLASE OF THE RPD3/HDA1 SUPERFAMILY 18; ATHDA18; histone deacetylase of the RPD3/HDA1 superfamily 18; MAF19.8; MAF19_8
NCBI Protein Information
histone deacetylase of the RPD3/HDA1 superfamily 18
NCBI Summary
Encodes a protein with similarity to histone deacetylases, a class of chromatin remodeling factors which act on H3/H4 histones. Expressed in roots where it appears to regulate the expression of epidermal cell fate genes controlling hair cell differentiation.
UniProt Protein Name
Histone deacetylase 18
UniProt Primary Accession #
Q8LRK8
UniProt Secondary Accession #
Q9FNQ7
UniProt Related Accession #
Q8LRK8
UniProt Comments
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Required for appropriate cellular patterning in the root epidermis. Histone deacetylases act via the formation of large multiprotein complexes .