NCBI Accession #
NP_567921.1
NCBI GenBank Nucleotide #
NM_119501.4
NCBI Official Full Name
histone deacetylase 14
NCBI Official Symbol
HDA14
NCBI Official Synonym Symbols
ATHDA14; F17M5.230; F17M5_230; histone deacetylase 14
NCBI Protein Information
histone deacetylase 14
NCBI Summary
Encodes HDA14, a member of the histone deacetylase family proteins that can deacetylate a-tubulin, associates with a/b-tubulin and is retained on GTP/taxol-stabilized microtubules, at least in part, by direct association with the PP2A-A2 subunit. The association of a histone deacetylase with PP2A suggests a direct link between protein phosphorylation and acetylation.
UniProt Protein Name
Histone deacetylase 14
UniProt Primary Accession #
Q941D6
UniProt Secondary Accession #
Q9SZC4
UniProt Related Accession #
Q941D6
UniProt Comments
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes .