NCBI Accession #
NP_196633.2
NCBI GenBank Nucleotide #
NM_121110.2
NCBI Official Full Name
histidine kinase 5
NCBI Official Synonym Symbols
AHK5; CKI2; CYTOKININ INDEPENDENT 2; histidine kinase 5; MAJ23.80; MAJ23_80
NCBI Protein Information
histidine kinase 5
NCBI Summary
member of Histidine Kinase
UniProt Synonym Gene Names
CKI2; AtHK5
UniProt Protein Name
Histidine kinase 5
UniProt Synonym Protein Names
Arabidopsis histidine kinase 5; AtHK5; Protein AUTHENTIC HIS-KINASE 5; Protein CYTOKININ-INDEPENDENT 2
UniProt Primary Accession #
Q3S4A7
UniProt Secondary Accession #
Q9FT60
UniProt Related Accession #
Q3S4A7
UniProt Comments
Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain. Negative regulator of the ETR1-dependent abscisic acid (ABA) and ethylene signaling pathway that inhibits the root elongation. Promotes stomatal closure. Regulates stomatal opening by integrating multiple signals via hydrogen peroxide H2O2 homeostasis in guard cells in an ABA-independent manner. May contribute to basal defense mechanisms by closing stomata in the presence of bacterial pathogens. Regulates both hormone levels and ROS production in response to stress. Required for full immunity to bacterial pathogen and necrotrophic fungus.