Histidine kinase 2 (AHK2), Recombinant Protein

Full Product Name

Recombinant Arabidopsis thaliana Histidine kinase 2 (AHK2) , partial

Product Gene Name

AHK2 recombinant protein

Product Synonym Gene Name

AHK2

Purity

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Molecular Weight

131,860 Da

Storage

Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

Protein Family

Histidine kinase

NCBI Accession #

NP_568532.1

NCBI GI #

18421494

NCBI GenBank Nucleotide #

NM_122966.3

NCBI GeneID

833552

NCBI Official Full Name

histidine kinase 2

NCBI Official Symbol

HK2

NCBI Official Synonym Symbols

AHK2; histidine kinase 2; MXH1.16; MXH1_16

NCBI Protein Information

histidine kinase 2

NCBI Summary

Encodes histidine kinase AHK2.

UniProt Gene Name

AHK2

UniProt Synonym Gene Names

AtHK2

UniProt Protein Name

Histidine kinase 2

UniProt Synonym Protein Names

Arabidopsis histidine kinase 2; AtHK2; Protein AUTHENTIC HIS-KINASE 2

UniProt Primary Accession #

Q9C5U2

UniProt Secondary Accession #

Q680Y4; Q8GUG0; Q9FKH3

UniProt Related Accession #

Q9C5U2

UniProt Comments

Cytokinins (CK) receptor related to bacterial two-component regulators. Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain. In the presence of cytokinin, feeds phosphate to phosphorelay-integrating histidine phosphotransfer protein (HPt) and activates subsequent cascade. Involved in meristems establishment in seedlings. Redundant negative regulator of drought and salt stress responses and abscisic acid (ABA) signaling. Together with AHK3, plays a negative regulatory role in cold stress signaling via inhibition of ABA response, occurring independently of the cold acclimation pathway. Redundant positive regulator of cytokinin signaling that regulates many developmental processes including seed germination, cell division, seed size, chlorophyll retention during leaf senescence, root repression and shoot promotion. Involved in alkamides (e.g. N-isobutyl decanamide) and N-acylethanolamides (NAE) signaling that control meristematic activity and differentiation processes during plant development. Contributes to vascular bundle formation and secondary growth in a cytokinin-dependent manner, probably by promoting the maintenance of mitotic activity and/or identity of procambial cells. Together with AHK4, required for growth and reproduction promotion stimulated by the endophytic fungus Piriformospora indica in a trans-zeatin-dependent manner. Required by the cytokinin-dependent flower development regulation pathway.