High mobility group B protein 1 (HMGB1), Recombinant Protein
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High mobility group B protein 1 (HMGB1), Recombinant Protein

Cat: RP04508
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana High mobility group B protein 1 (HMGB1)
Product Gene Name
HMGB1 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MKTAKGKDKV KTTKEALKPV DDRKVGKRKA PAEKPTKRET RKEKKAKKDP NKPKRAPSAF FVFLEDFRVT FKKENPNVKA VSAVGKAGGQ KWKSMSQAEK APYEEKAAKR KAEYEKQMDA YNKNLEEGSD ESEKSRSEIN DEDEASGEEE LLEKEAAGDD EEEEEEEDDD DDDDEEED
Sequence Positions
1-178, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
20,990 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
High mobility group protein

NCBI/Uniprot Data

NCBI Accession #
NP_001078269.1
NCBI GI #
145332807
NCBI GenBank Nucleotide #
NM_001084800.2
NCBI GeneID
824351
NCBI Official Full Name
high mobility group B1
NCBI Official Symbol
HMGB1
NCBI Official Synonym Symbols
AtHMGB1; high mobility group B1; NFD1; NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR D1
NCBI Protein Information
high mobility group B1
NCBI Summary
Encodes a protein belonging to the subgroup of HMGB (high mobility group B) proteins that have a distinctive DNA-binding motif, the HMG-box domain. The motif confers non-sequence specific interaction with linear DNA and structure-specific binding to distorted DNA sites. The HMGB proteins are involved in the assembly of nucleoprotein complexes. Can be phosphorylated by CK2alpha. In interphase cells, HMGB1 is found throughout the nucleus, whereas in mitotic cells it is not chromatin-associated.
UniProt Gene Name
HMGB1
UniProt Synonym Gene Names
HMGA; HMGALPHA; NFD01; NFD1; ORF13; AtHMGalpha; HMG alpha; Nucleosome/chromatin assembly factor group D 1
UniProt Protein Name
High mobility group B protein 1
UniProt Synonym Protein Names
High mobility group protein A; AtHMGalpha; HMG alpha; Nucleosome/chromatin assembly factor group D 01; Nucleosome/chromatin assembly factor group D 1
UniProt Primary Accession #
O49595
UniProt Secondary Accession #
Q3EAL6
UniProt Related Accession #
O49595
UniProt Comments
Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses.

For research use only, not for clinical use.