NCBI Accession #
NP_001078269.1
NCBI GenBank Nucleotide #
NM_001084800.2
NCBI Official Full Name
high mobility group B1
NCBI Official Symbol
HMGB1
NCBI Official Synonym Symbols
AtHMGB1; high mobility group B1; NFD1; NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR D1
NCBI Protein Information
high mobility group B1
NCBI Summary
Encodes a protein belonging to the subgroup of HMGB (high mobility group B) proteins that have a distinctive DNA-binding motif, the HMG-box domain. The motif confers non-sequence specific interaction with linear DNA and structure-specific binding to distorted DNA sites. The HMGB proteins are involved in the assembly of nucleoprotein complexes. Can be phosphorylated by CK2alpha. In interphase cells, HMGB1 is found throughout the nucleus, whereas in mitotic cells it is not chromatin-associated.
UniProt Synonym Gene Names
HMGA; HMGALPHA; NFD01; NFD1; ORF13; AtHMGalpha; HMG alpha; Nucleosome/chromatin assembly factor group D 1
UniProt Protein Name
High mobility group B protein 1
UniProt Synonym Protein Names
High mobility group protein A; AtHMGalpha; HMG alpha; Nucleosome/chromatin assembly factor group D 01; Nucleosome/chromatin assembly factor group D 1
UniProt Primary Accession #
O49595
UniProt Secondary Accession #
Q3EAL6
UniProt Related Accession #
O49595
UniProt Comments
Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses.