NCBI Accession #
NP_179960.1
NCBI GenBank Nucleotide #
NM_127943.3
NCBI Official Full Name
geranylgeranyl pyrophosphate synthase 2
NCBI Official Symbol
GGPS2
NCBI Official Synonym Symbols
F27L4.2; F27L4_2; geranylgeranyl pyrophosphate synthase 2; GERANYLGERANYL PYROPHOSPHATE SYNTHASE 5; GGPS5; PREGERANYLGERANYL PYROPHOSPHATE SYNTHASE
NCBI Protein Information
geranylgeranyl pyrophosphate synthase 2
NCBI Summary
encodes an endoplasmic reticulum-targeted geranylgeranyl pyrophosphate synthase
UniProt Synonym Gene Names
GGPP5; GGPS2; GGPP synthase 2; GGPS2
UniProt Protein Name
Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 2
UniProt Synonym Protein Names
(2E,6E)-farnesyl diphosphate synthase 2; Dimethylallyltranstransferase 2 (EC:2.5.1.1); Farnesyl diphosphate synthase 2; Farnesyltranstransferase 2 (EC:2.5.1.29); Geranyltranstransferase 2 (EC:2.5.1.10)
UniProt Primary Accession #
O04046
UniProt Secondary Accession #
Q38917; Q7DN59
UniProt Related Accession #
O04046
UniProt Comments
Heterodimeric geranyl(geranyl)-diphosphate (GPP) synthase large subunit. In vitro, the large subunit catalyzes mainly the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate while the small subunit alone is inactive. Upon association of the two subunits, the product profile is not changed.