NCBI Accession #
NP_195399.1
NCBI GenBank Nucleotide #
NM_119845.3
NCBI Official Full Name
geranylgeranyl pyrophosphate synthase 1
NCBI Official Symbol
GGPS1
NCBI Official Synonym Symbols
AtGGPPS11; AtLSU; geranyl(geranyl)diphosphate synthase 11; geranylgeranyl pyrophosphate synthase 1; GGPPS11; Large subunit of Heterodimeric geranyl(geranyl)diphosphate synthase; LSU
NCBI Protein Information
geranylgeranyl pyrophosphate synthase 1
NCBI Summary
Encodes a protein with geranylgeranyl pyrophosphate synthase activity involved in isoprenoid biosynthesis. The enzyme appears to be targeted to the chloroplast in epidermal cells and guard cells of leaves, and in etioplasts in roots.
UniProt Synonym Gene Names
GGPPS11; GGPS1; GGPP synthase 1; GGPS1
UniProt Protein Name
Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 1, chloroplastic
UniProt Synonym Protein Names
(2E,6E)-farnesyl diphosphate synthase 1; Dimethylallyltranstransferase 1 (EC:2.5.1.1); Farnesyl diphosphate synthase 1; Farnesyltranstransferase 1 (EC:2.5.1.29); Geranyltranstransferase 1 (EC:2.5.1.10)
UniProt Primary Accession #
P34802
UniProt Secondary Accession #
O23201
UniProt Related Accession #
P34802
UniProt Comments
Heterodimeric geranyl(geranyl)-diphosphate (GPP) synthase large subunit. In vitro, the large subunit catalyzes mainly the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate while the small subunit alone is inactive. Upon association of the two subunits, the product profile changes and the production of gerany-diphosphate is strongly increased.