NCBI Accession #
NP_198206.1
NCBI GenBank Nucleotide #
NM_122737.4
NCBI Official Full Name
heat shock protein 70 (Hsp 70) family protein
NCBI Official Symbol
BIP1
NCBI Official Synonym Symbols
T26D3.10; T26D3_10
NCBI Protein Information
heat shock protein 70 (Hsp 70) family protein
NCBI Summary
Encodes the luminal binding protein BiP, an ER-localized member of the HSP70 family. BiP is composed of an N-terminal ATP binding domain and a C-terminal domain that binds to hydrophobic patches on improperly/incompletely folded proteins in an ATP-dependent manner. Involved in polar nuclei fusion during proliferation of endosperm nuclei.
UniProt Synonym Gene Names
BIP1; HSP70-11; MED37_5; AtHsp70-11; AtBP1; BiP1
UniProt Protein Name
Mediator of RNA polymerase II transcription subunit 37a
UniProt Synonym Protein Names
Heat shock 70 kDa protein 11; Heat shock protein 70-11; AtHsp70-11; Luminal-binding protein 1; AtBP1; BiP1
UniProt Primary Accession #
Q9LKR3
UniProt Secondary Accession #
Q41928; Q56Y82
UniProt Related Accession #
Q9LKR3
UniProt Comments
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.