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Guard cell S-type anion channel SLAC1 (SLAC1), Recombinant Protein
Cat: RP06219
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Guard cell S-type anion channel SLAC1 (SLAC1) , partial
Product Gene Name
SLAC1 recombinant protein
Product Synonym Gene Name
SLAC1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
63,235 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Guard cell S-type anion channel
NCBI/Uniprot Data
NCBI Accession #
NP_563909.1
NCBI GI #
18391400
NCBI GenBank Nucleotide #
NM_101120.3
NCBI GeneID
837805
NCBI Official Full Name
C4-dicarboxylate transporter/malic acid transport protein
NCBI Official Symbol
OZS1
NCBI Official Synonym Symbols
CARBON DIOXIDE INSENSITIVE 3; CDI3; F5O11.23; F5O11_23; OZONE-SENSITIVE 1; RADICAL-INDUCED CELL DEATH 3; RCD3; SLAC1; SLOW ANION CHANNEL-ASSOCIATED 1
NCBI Protein Information
C4-dicarboxylate transporter/malic acid transport protein
NCBI Summary
Encodes a membrane protein with 10 predicted transmembrane helices. SLAC1 is a multispanning membrane protein expressed predominantly in guard cells that plays a role in regulating cellular ion homeostasis and S-type anion currents. SLAC1 is important for normal stomatal closure in response to a variety of signals including elevated CO2, ozone, ABA, darkness, and humidity. SLAC1:GFP localizes to the plasma membrane.
UniProt Gene Name
SLAC1
UniProt Synonym Gene Names
CDI3; OZS1; RCD3
UniProt Protein Name
Guard cell S-type anion channel SLAC1
UniProt Synonym Protein Names
Protein CARBON DIOXIDE INSENSITIVE 3; Protein OZONE-SENSITIVE 1; Protein RADICAL-INDUCED CELL DEATH 3; Protein SLOW ANION CHANNEL-ASSOCIATED 1
UniProt Primary Accession #
Q9LD83
UniProt Related Accession #
Q9LD83
UniProt Comments
Slow, weak voltage-dependent S-type anion efflux channel involved in maintenance of anion homeostasis. Cl- efflux through SLAC1 causes membrane depolarization, which activates outward-rectifying K1 channels, leading to KCl and water efflux to reduce turgor further and cause stomatal closure, that reduces water loss and promotes leaf turgor. Essential for stomatal closure in response to CO2, abscisic acid (ABA), ozone O3, light/dark transitions, humidity change, calcium ions, hydrogen peroxide H2O2, reactive oxygen species (ROS), and nitric oxide. Binds to the highly selective inward-rectifying potassium channels KAT1 and AKT2, and inhibits their actvities. Functions as an essential negative regulator of inward potassium channels in guard cells. Essential for the efficient stomatal closure and opening in guard cells (PubMed:27002025).
For research use only, not for clinical use.