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GPA1, Recombinant Protein
Cat: RP03744
Size: 0.05 mg/ 0.1 mg/ 5x0.1 mg
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Mouse-ear cress GPA1 protein, N-His Tag
Product Synonym Names
GP-alpha-1; Guanine nucleotide-binding protein alpha-1 subunit; GPA1
Product Gene Name
GPA1 recombinant protein
Purity
>90% as determined by SDS-PAGE
Format
Lyophilized. Lyophilized from PBS pH 7.4, 0.2% NLS, 5% Trehalose, 5% Mannose, 1mM EDTA.
Host
E Coli
Molecular Weight
44,546 Da
Storage
Store at 2 to 8℃ for one week. Store at -20 to -80℃ for twelve months from the date of receipt. Use a manual defrost freezer and avoid repeated freeze thaw cycles.In general, proteins are provided as lyophilized powder or frozen liquid. They are shipped out with dry ice or blue ice unless customers require otherwise.
NCBI/Uniprot Data
NCBI Accession #
NP_001325056.1
NCBI GI #
1063704930
NCBI GenBank Nucleotide #
NM_001336055.1
NCBI GeneID
817170
NCBI Official Full Name
G protein alpha subunit 1
NCBI Official Symbol
GP ALPHA 1
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA G PROTEIN ALPHA SUBUNIT 1; ATGPA1; G PROTEIN ALPHA SUBUNIT; G protein alpha subunit 1; G PROTEIN ALPHA SUBUNIT 1; GPA1; T1D16.6; T1D16_6
NCBI Protein Information
G protein alpha subunit 1
NCBI Summary
Encodes an alpha subunit of a heterotrimeric GTP-binding protein. The active GTP-bound form of GPA1 binds to the GTG1 and GTG2 abscisic acid (ABA) receptors and appears to affect their GTPase and GTP-binding activity, and hence, ABA binding abilities. GPA1 is a positive regulator in ABA-mediated inhibition of stomatal opening. Plants with recessive mutant alleles have complex phenotypes including: reduced brassinolide response, reduced cell divisions, round leaves, short hypocotyls. It is likely to be involved in the signaling events that trigger unfolded protein response-associated cell death. GPA1 is also involved in sugar signaling.
UniProt Gene Name
GPA1
UniProt Synonym Gene Names
GP-alpha-1
UniProt Protein Name
Guanine nucleotide-binding protein alpha-1 subunit
UniProt Primary Accession #
P18064
UniProt Related Accession #
P18064
UniProt Comments
Exhibits a fast rate of basal nucleotide exchange. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Together with GCR1, may regulate the cell cycle via a signaling cascade that uses phosphatidylinositol-specific phospholipase C (PI-PLC) as an effector and inositol 1,4,5-trisphosphate (IP3) as a second messenger. Promotes abscisic acid (ABA) responses in guard cells. But, together with GCR1 and GB1, acts as a negative regulator of ABA during seed germination and early seedling development. Involved in the blue light (BL) signaling. Together with GCR1 and ADT3, required for BL-mediated synthesis of phenylpyruvate and subsequently of phenylalanine (Phe), in etiolated seedlings. Modulates root architecture (e.g. lateral root formation). Negatively regulated by RGS1.
For research use only, not for clinical use.