NCBI Accession #
NP_001330361.1
NCBI GenBank Nucleotide #
NM_001344352.1
NCBI Official Full Name
glucose-6-phosphate dehydrogenase 6
NCBI Official Symbol
G6PD6
NCBI Official Synonym Symbols
glucose-6-phosphate dehydrogenase 6; K1B16.1; K1B16_1
NCBI Protein Information
glucose-6-phosphate dehydrogenase 6
NCBI Summary
Encodes a cytosolic glucose-6-phosphate dehydrogenase that is insensitive to reduction by DTT and whose mRNA is expressed ubiquitously.
UniProt Synonym Gene Names
G6PD6
UniProt Protein Name
Glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform 2
UniProt Synonym Protein Names
G6PDH6; G6PD6
UniProt Primary Accession #
Q9FJI5
UniProt Secondary Accession #
Q9SUJ9
UniProt Related Accession #
Q9FJI5
UniProt Comments
Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis which are involved in membrane synthesis and cell division.