NCBI Accession #
NP_175032.1
NCBI GenBank Nucleotide #
NM_103492.5
NCBI Official Full Name
Inositol monophosphatase family protein
NCBI Official Synonym Symbols
6-bisphosphatase; Arabidopsis thaliana cytosolic fructose-1; AtcFBP; F2J6.2; F2J6_2; FINS1; FRUCTOSE INSENSITIVE 1; fructose-1
NCBI Protein Information
Inositol monophosphatase family protein
NCBI Summary
Encodes a fructose-1,6-bisphosphatase. This enzyme, in addition to catalyzing the formation of fructose-6-phosphate for sucrose biosynthesis, appears to play a role in fructose-mediated signaling that is independent of its enzymatic activity. atcfbp-1/fins1 mutants have reduced photosynthetic rates, elevated levels of starch and reduced levels of sucrose during the day. Although the protein is expected to be cytosolic, a GFP-tagged version localizes to the cytoplasm and the nucleus.
UniProt Synonym Gene Names
FBPaseCurated
UniProt Protein Name
Fructose-1,6-bisphosphatase, cytosolic
UniProt Synonym Protein Names
D-fructose-1,6-bisphosphate 1-phosphohydrolase
UniProt Primary Accession #
Q9MA79
UniProt Related Accession #
Q9MA79
UniProt Comments
Catalyzes the first irreversible reaction from fructose-1,6-bisphosphate to fructose-6-phosphate and inorganic phosphate and plays an important regulatory role in sucrose biosynthesis and metabolism (Probable). Its activity is essential to regulate starch levels (PubMed:25743161). Functions in fructose-mediated signaling independently of its catalytic activity in sugar metabolism. May act downstream of ABA2/GIN1, which is involved in abscisic acid (ABA) synthesis to regulate autotrophic transition and modulate early seedling establishment after seed germination (PubMed:21253566).