Folylpolyglutamate synthase (FPGS3), Recombinant Protein
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Folylpolyglutamate synthase (FPGS3), Recombinant Protein

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Cat: RP06069
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Folylpolyglutamate synthase (FPGS3)
Product Gene Name
FPGS3 recombinant protein
Product Synonym Gene Name
FPGS3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MATEDDGELS ARYQNTLDAL SSLITKRGRL ASNNQSHRFR LLFHYLKVLE LEDAVSQMKI IHVAGTKGKG STCTFAESIL RCYGLRTGLF TSPHLIDVRE RFRLNGIEIS QEKFVNYFWC CFHKLKEKTS NEVPMPTYFC FLALLAFKIF TTEQVDVVIL EVGLGGRFDA TNVIQKPVVC GISSLGYDHM EILGYTLAEI AAEKAGIFKS GVPAFTVAQP DEAMRVLNEK ASKLEVNLQV VEPLDSSQRL GLQGEHQYLN AGLAVALCST FLKEIGIEDK NGLDQTNGLP EKFISGLSNA YLMGRAMIVP DSELPEEIVY YLDGAHSPES MEACAIWFSK QIKQNQERNQ KRSEQILLFN CMSVRDPSLL LPRLRSKCID QGVDFKRAVF VPNVSVYNQV GSSTNVGTRV ESMSWQFGLQ RIWESLARGE AKSNSKSDSK GKEEEKSFVF SSLPVAVDWL RDNARQSKQV RFQVLVTGSL HLVGDLLRFI KK
Sequence Positions
1-492, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
52,604 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_567026.3
NCBI GI #
30694288
NCBI GenBank Nucleotide #
NM_115421.4
NCBI GeneID
824729
NCBI Official Full Name
DHFS-FPGS homolog D
NCBI Official Symbol
DFD
NCBI Official Synonym Symbols
ATDFD; DHFS-FPGS homolog D; folylpolyglutamate synthetase 3; FPGS3
NCBI Protein Information
DHFS-FPGS homolog D
NCBI Summary
Encodes one of the three folylpolyglutamate synthetase isoforms (FPGSs): FPGS1 (At5g05980, plastidic), FPGS2 (At3g10160, mitochondrial) and FPGS3 (At3g55630, cytosolic).
UniProt Gene Name
FPGS3
UniProt Synonym Gene Names
Tetrahydrofolate synthase
UniProt Protein Name
Folylpolyglutamate synthase
UniProt Synonym Protein Names
DHFS-FPGS homolog D
UniProt Primary Accession #
Q8W035
UniProt Secondary Accession #
Q8LD20; Q93Y54; Q9M059; F4IWY4
UniProt Related Accession #
Q8W035
UniProt Comments
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Essential for organellar and whole-plant folate homeostasis.

For research use only, not for clinical use.