Folylpolyglutamate synthase (FPGS2), Recombinant Protein
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Folylpolyglutamate synthase (FPGS2), Recombinant Protein

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Cat: RP04430
Size: 0.5 mg (E-Coli)/ 0.05 mg (Baculovirus)/ 0.5 mg (Yeast)/ 0.05 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Folylpolyglutamate synthase (FPGS2) , partial
Product Gene Name
FPGS2 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MATEDDGELS ARYQNTLDAL SSLITKRGRL ASNNQSHRFR LLFHYLKVLE LEDAVSQMKI IHVAGTKGKG STCTFAESIL RCYGLRTGLF TSPHLIDVRE RFRLNGIEIS QEKFVNYFWC CFHKLKEKTS NEVPMPTYFC FLALLAFKIF TTEQVDVVIL EVGLGGRFDA TNVIQKPVVC GISSLGYDHM EILGYTLAEI AAEKAGIFKS GVPAFTVAQP DEAMRVLNEK ASKLEVNLQV VEPLDSSQRL GLQGEHQYLN AGLAVALCST FLKEIGIEDK NGLDQTNGLP EKFISGLSNA YLMGRAMIVP DSELPEEIVY YLDGAHSPES MEACAIWFSK QIKQNQERNQ KRSEQILLFN CMSVRDPSLL LPRLRSKCID QGVDFKRAVF VPNVSVYNQV GSSTNVGTRV ESMSWQFGLQ RIWESLARGE AKSNSKSDSK GKEEEKSFVF SSLPVAVDWL RDNARQSKQV RFQVLVTGSL HLVGDLLRFI KK
Sequence Positions
1-492
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
68,921 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_187627.3
NCBI GI #
79396625
NCBI GenBank Nucleotide #
NM_111851.6
NCBI GeneID
820179
NCBI Official Full Name
DHFS-FPGS homolog C
NCBI Official Symbol
DFC
NCBI Official Synonym Symbols
A. THALIANA DHFS-FPGS HOMOLOG C; ATDFC; DHFS-FPGS homolog C; folylpolyglutamate synthetase 2; FPGS2
NCBI Protein Information
DHFS-FPGS homolog C
NCBI Summary
Encodes a protein with tetrahydrofolylpolyglutamate synthase activity that is located in the mitochondrial matrix. One of the three folylpolyglutamate synthetase isoforms (FPGSs): FPGS1 (At5g05980, plastidic), FPGS2 (At3g10160, mitochondrial) and FPGS3 (At3g55630, cytosolic).
UniProt Gene Name
FPGS2
UniProt Synonym Gene Names
Tetrahydrofolate synthase
UniProt Protein Name
Folylpolyglutamate synthase
UniProt Synonym Protein Names
DHFS-FPGS homolog C
UniProt Primary Accession #
F4J2K2
UniProt Secondary Accession #
Q8W038; Q9SR80; A2RVP0
UniProt Related Accession #
F4J2K2
UniProt Comments
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Essential for organellar and whole-plant folate homeostasis.

For research use only, not for clinical use.