Folylpolyglutamate synthase (FPGS1), Recombinant Protein
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Folylpolyglutamate synthase (FPGS1), Recombinant Protein

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Cat: RP06320
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Folylpolyglutamate synthase (FPGS1) , partial
Product Gene Name
FPGS1 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
56,638 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Folylpolyglutamate synthase

NCBI/Uniprot Data

NCBI Accession #
NP_001031840.1
NCBI GI #
79327065
NCBI GenBank Nucleotide #
NM_001036763.2
NCBI GeneID
830484
NCBI Official Full Name
DHFS-FPGS homolog B
NCBI Official Symbol
DFB
NCBI Official Synonym Symbols
ATDFB; DHFS-FPGS homolog B; folylpolyglutamate synthetase 1; FPGS1; K18J17.17; K18J17_17
NCBI Protein Information
DHFS-FPGS homolog B
NCBI Summary
Encodes one of the three folylpolyglutamate synthetase isoforms (FPGSs): FPGS1 (At5g05980, plastidic), FPGS2 (At3g10160, mitochondrial) and FPGS3 (At3g55630, cytosolic).
UniProt Gene Name
FPGS1
UniProt Synonym Gene Names
Tetrahydrofolate synthase
UniProt Protein Name
Folylpolyglutamate synthase
UniProt Synonym Protein Names
DHFS-FPGS homolog B
UniProt Primary Accession #
F4K2A1
UniProt Secondary Accession #
Q8W040; Q9FI88; B9DH96; F4K2A2
UniProt Related Accession #
F4K2A1
UniProt Comments
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Essential for organellar and whole-plant folate homeostasis. Required for postembryonic root development. Generates polyglutamylated folate cofactors to support C1 metabolism required for meristem maintenance and cell expansion during postembryonic root development.

For research use only, not for clinical use.