FACT complex subunit SSRP1 (SSRP1), Recombinant Protein

Full Product Name

Recombinant Zea mays FACT complex subunit SSRP1 (SSRP1), partial

Product Gene Name

SSRP1 recombinant protein

Product Synonym Gene Name

SSRP1

Purity

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Molecular Weight

71,418 Da

Storage

Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI Accession #

Q9LEF5.1

NCBI GI #

75263808

NCBI Official Full Name

FACT complex subunit SSRP1

UniProt Gene Name

SSRP1

UniProt Protein Name

FACT complex subunit SSRP1

UniProt Synonym Protein Names

Facilitates chromatin transcription complex subunit SSRP1; Recombination signal sequence recognition protein 1; Zm-SSRP1

UniProt Primary Accession #

Q9LEF5

UniProt Comments

Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II . Binds specifically to double-stranded DNA.