NCBI Accession #
                                                
                                                
                                                    NP_199628.1                                                
                                             
                                                                                    
                                                                                    
                                                
                                                    NCBI GenBank Nucleotide #
                                                
                                                
                                                    NM_124191.4                                                
                                             
                                                                                    
                                                                                    
                                                
                                                    NCBI Official Full Name
                                                
                                                
                                                    F-box family protein                                                
                                             
                                                                                    
                                                
                                                    NCBI Official Symbol
                                                
                                                
                                                    SLY2                                                
                                             
                                                                                    
                                                
                                                    NCBI Official Synonym Symbols
                                                
                                                
                                                    MIF21.6; MIF21_6; SLEEPY2; SNE; SNEEZY                                                
                                             
                                                                                    
                                                
                                                    NCBI Protein Information
                                                
                                                
                                                    F-box family protein                                                
                                             
                                                                                    
                                                
                                                    NCBI Summary
                                                
                                                
                                                    encodes an F-box protein whose protein sequence is similar to SLY1, which belongs to SCF-SLY1 E3 ligase complex. SCF-SLY1 E3 ligase degrades DELLA proteins that are involved in promoting growth. Overexpression of SLY2 can partially compensate sly1-10 mutant phenotype of dwarfism.                                                
                                             
                                                                                    
                                                                                    
                                                
                                                    UniProt Synonym Gene Names
                                                
                                                
                                                    SLY2                                                
                                             
                                                                                    
                                                
                                                    UniProt Protein Name
                                                
                                                
                                                    F-box protein SNE                                                
                                             
                                                                                    
                                                
                                                    UniProt Synonym Protein Names
                                                
                                                
                                                    Protein SNEEZY; Sleepy protein 2                                                
                                             
                                                                                    
                                                
                                                    UniProt Primary Accession #
                                                
                                                
                                                    Q9LUB6                                                
                                             
                                                                                    
                                                
                                                    UniProt Related Accession #
                                                
                                                
                                                    Q9LUB6                                                
                                             
                                                                                    
                                                
                                                    UniProt Comments
                                                
                                                
                                                    Essential component of a SCF-type E3 ligase complex that positively regulates the gibberellin signaling pathway. Upon gibberellin treatment, such complex probably mediates the ubiquitination and subsequent degradation of DELLA proteins (GAI, RGA and RGL2), some repressors of the gibberellin pathway, leading to activate the pathway. Can partially complement the absence of GID2/SLY1.