F-box protein SKP2B (SKP2B), Recombinant Protein
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F-box protein SKP2B (SKP2B), Recombinant Protein

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Cat: RP04052
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana F-box protein SKP2B (SKP2B)
Product Gene Name
SKP2B recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MVSEGATRKE LNLCFENMKM EGVLISEWKD IPVELLMKIL NLVDDRTVII ASCICSGWRD AVSLGLTRLS LSWCKKNMNS LVLSLAPKFV KLQTLVLRQD KPQLEDNAVE AIANHCHELQ DLDLSKSSKI TDHSLYSLAR GCTNLTKLNL SGCTSFSDTA LAHLTRFCRK LKILNLCGCV EAVSDNTLQA IGENCNQLQS LNLGWCENIS DDGVMSLAYG CPDLRTLDLC SCVLITDESV VALANRCIHL RSLGLYYCRN ITDRAMYSLA QSGVKNKHEM WRAVKKGKFD EEGLRSLNIS QCTYLTPSAV QAVCDTFPAL HTCSGRHSLV MSGCLNLQSV HCACILQAHR THTVYPHPAH
Sequence Positions
1-360, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
39,909 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
F-box protein

NCBI/Uniprot Data

NCBI Accession #
NP_001185415.1
NCBI GI #
334183953
NCBI GenBank Nucleotide #
NM_001198486.2
NCBI GeneID
844036
NCBI Official Full Name
RNI-like superfamily protein
NCBI Official Symbol
SKP2B
NCBI Official Synonym Symbols
ARABIDOPSIS HOMOLOG OF HOMOLOG OF HUMAN SKP2 2; ATSKP2;2; F22K20.10; F22K20_10
NCBI Protein Information
RNI-like superfamily protein
NCBI Summary
AtSKP2;2 is a homolog of human SKP2, the human F-box protein that recruits E2F1. Contains an F-box motif at the N-terminal region and a C-terminal Leu-rich repeat domain. Forms part of an E3-ubiquitin-ligase SCF (Skp1, cullin, F-box) complex and recruits phosphorylated AtE2Fc, a transcriptional factor that might play a role in cell division and during the transition from skotomorphogenesis to photomorphogenesis. AtSKP2;1 (At1g21410) and AtSKP2;2 (At1g77000) may be duplicated genes. AtSKP2b may also be involved in the degradation of KRP1/ICK1, a CDK inhibitor.
UniProt Gene Name
SKP2B
UniProt Synonym Gene Names
FBL5; AtFB5; AtSKP2;2
UniProt Protein Name
F-box protein SKP2B
UniProt Synonym Protein Names
F-box/LRR-repeat protein 5; AtFB5; SKP2-like protein 2; AtSKP2;2
UniProt Primary Accession #
O49286
UniProt Secondary Accession #
Q680E2; Q8GY48
UniProt Related Accession #
O49286
UniProt Comments
Component of SCF(SKP2B) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of the cyclin-dependent kinase inhibitor KRP1. Does not interact with auxin.

For research use only, not for clinical use.