F-box protein SKP2A (SKP2A), Recombinant Protein
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F-box protein SKP2A (SKP2A), Recombinant Protein

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Cat: RP04182
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana F-box protein SKP2A (SKP2A)
Product Gene Name
SKP2A recombinant protein
Product Synonym Gene Name
SKP2A
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MVMGGEASME LDQCFQKMKM EGISIKEWKD IPVELLMRIL SLVDDRNVIV ASGVCTGWRD AISFGLTRLR LSWCNNNMNS LVLSLVPKFV KLQTLNLRQD KPQLEDNAVE AIANHCHELQ ELDLSKSLKI TDRSLYALAH GCPDLTKLNL SGCTSFSDTA IAYLTRFCRK LKVLNLCGCV KAVTDNALEA IGNNCNQMQS LNLGWCENIS DDGVMSLAYG CPDLRTLDLC GCVLITDESV VALADWCVHL RSLGLYYCRN ITDRAMYSLA QSGVKNKPGS WKSVKKGKYD EEGLRSLNIS QCTALTPSAV QAVCDSFPAL HTCSGRHSLV MSGCLNLTTV HCACILQAHR AHNAVPHPAH
Sequence Positions
1-360, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
39,614 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
F-box protein

NCBI/Uniprot Data

NCBI Accession #
NP_001321134.1
NCBI GI #
1063685348
NCBI GenBank Nucleotide #
NM_001332504.1
NCBI GeneID
838740
NCBI Official Full Name
F-box/RNI-like superfamily protein
NCBI Official Symbol
SKP2A
NCBI Official Synonym Symbols
F24J8.5; F24J8_5
NCBI Protein Information
F-box/RNI-like superfamily protein
NCBI Summary
AtSKP2;1 is a homolog of human SKP2, the human F-box protein that recruits E2F1. Contains an F-box motif at the N-terminal region and a C-terminal Leu-rich repeat domain. Forms part of an E3-ubiquitin-ligase SCF (Skp1, cullin, F-box) complex and recruits phosphorylated AtE2Fc, a transcriptional factor that might play a role in cell division and during the transition from skotomorphogenesis to photomorphogenesis. AtSKP2;1 (At1g21410) and AtSKP2;2 (At1g77000) may be duplicated genes.
UniProt Gene Name
SKP2A
UniProt Synonym Gene Names
AtFBL5; AtSKP2;1
UniProt Protein Name
F-box protein SKP2A
UniProt Synonym Protein Names
FBL5-like protein; AtFBL5; SKP2-like protein 1; AtSKP2;1
UniProt Primary Accession #
Q9LPL4
UniProt Secondary Accession #
Q8LDN3
UniProt Related Accession #
Q9LPL4
UniProt Comments
Component of SCF(SKP2A) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (including cell cycle repressors). Acts as an auxin receptor. Regulates the stability of the transcription factors E2FC and DPB, repressors of cell proliferation. Confers increase tolerance to osmotic stress by promoting cell division, especially in meristems. Promotes the formation of lateral root primordia.

For research use only, not for clinical use.