NCBI Accession #
NP_175829.1
NCBI GenBank Nucleotide #
NM_104305.4
NCBI Official Full Name
eif4a-2
NCBI Official Symbol
EIF4A-2
NCBI Official Synonym Symbols
eif4a-2; F20D21.9; F20D21_9
NCBI Protein Information
eif4a-2
NCBI Summary
member of eIF4A - eukaryotic initiation factor 4A
UniProt Gene Name
TIF4A-2
UniProt Synonym Gene Names
RH19; eIF-4A-2
UniProt Protein Name
Eukaryotic initiation factor 4A-2
UniProt Synonym Protein Names
ATP-dependent RNA helicase eIF4A-2; DEAD-box ATP-dependent RNA helicase 19
UniProt Primary Accession #
P41377
UniProt Secondary Accession #
Q0WWK5
UniProt Related Accession #
P41377
UniProt Comments
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon .