NCBI Accession #
NP_179685.1
NCBI GenBank Nucleotide #
NM_127658.4
NCBI Official Full Name
Integrase-type DNA-binding superfamily protein
NCBI Official Symbol
ERF53
NCBI Official Synonym Symbols
AtERF53; ERF domain 53; F5H14.15; F5H14_15
NCBI Protein Information
Integrase-type DNA-binding superfamily protein
NCBI Summary
Encodes ERF53, a drought-induced transcription factor. Belongs to the AP2/ERF superfamily, and has a highly conserved AP2 domain. Regulates drought-responsive gene expressions by binding to the GCC box and/or dehydration-responsive element (DRE) in the promoter of downstream genes. Overexpression of AtERF53 driven by the CaMV35S promoter resulted in an unstable drought-tolerant phenotype in T2 transgenic plants.
UniProt Synonym Gene Names
AtERF53
UniProt Protein Name
Ethylene-responsive transcription factor ERF053
UniProt Primary Accession #
Q9SKT1
UniProt Related Accession #
Q9SKT1
UniProt Comments
Transcriptional activator involved in abiotic stress tolerance. Can directly regulate stress-related gene expression by binding to the DNA sequence 5'-[AG]CCGAC-3' (DRE element) of their promoter region. Involved in the regulation of stomatal closure movement under drought stress (PubMed:23625358). Acts as a positive regulator of drought stress response (PubMed:22095047).