Ethylene-responsive transcription factor ABI4 (ABI4), Recombinant Protein

Full Product Name

Recombinant Arabidopsis thaliana Ethylene-responsive transcription factor ABI4 (ABI4)

Product Gene Name

ABI4 recombinant protein

Purity

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Sequence

MDPLASQHQH NHLEDNNQTL THNNPQSDST TDSSTSSAQR KRKGKGGPDN SKFRYRGVRQ RSWGKWVAEI REPRKRTRKW LGTFATAEDA ARAYDRAAVY LYGSRAQLNL TPSSPSSVSS SSSSVSAASS PSTSSSSTQT LRPLLPRPAA ATVGGGANFG PYGIPFNNNI FLNGGTSMLC PSYGFFPQQQ QQQNQMVQMG QFQHQQYQNL HSNTNNNKIS DIELTDVPVT NSTSFHHEVA LGQEQGGSGC NNNSSMEDLN SLAGSVGSSL SITHPPPLVD PVCSMGLDPG YMVGDGSSTI WPFGGEEEYS HNWGSIWDFI DPILGEFY

Sequence Positions

1-328, Full length protein

Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Molecular Weight

35,671 Da

Storage

Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

Protein Family

Ethylene-responsive transcription factor

NCBI Accession #

NP_181551.1

NCBI GI #

15225661

NCBI GenBank Nucleotide #

NM_129580.2

NCBI GeneID

818614

NCBI Official Full Name

Integrase-type DNA-binding superfamily protein

NCBI Official Symbol

ABI4

NCBI Official Synonym Symbols

ABA INSENSITIVE 4; ABSCISIC ACID-INSENSITIVE PROTEIN 4; ATABI4; GIN6; GLUCOSE INSENSITIVE 6; IMPAIRED SUCROSE INDUCTION 3; ISI3; SALOBRENO 5; SAN5; SIS5; SUCROSE UNCOUPLED 6; SUGAR-INSENSITIVE 5; SUN6; T7M7.16

NCBI Protein Information

Integrase-type DNA-binding superfamily protein

NCBI Summary

Encodes a member of the DREB subfamily A-3 of ERF/AP2 transcription factor family (ABI4). The protein contains one AP2 domain. There is only one member in this family. Involved in abscisic acid (ABA) signal transduction, ABA-mediated glucose response, and hexokinase-dependent sugar responses. Acts downstream of GUN1 in retrograde signaling. Expressed most abundantly in developing siliques and to a lesser degree in seedlings.

UniProt Gene Name

ABI4

UniProt Synonym Gene Names

ERF ABI4

UniProt Protein Name

Ethylene-responsive transcription factor ABI4

UniProt Synonym Protein Names

Protein ABSCISIC ACID INSENSITIVE 4

UniProt Primary Accession #

A0MES8

UniProt Secondary Accession #

O81138; Q6J9N5

UniProt Related Accession #

A0MES8

UniProt Comments

Transcription regulator that probably binds to the GCC-box pathogenesis-related promoter element. Binds also to the S-box (5'-CACTTCCA-3') photosynthesis-associated nuclear genes-related (PhANGs-related) promoter element, and thus acts as a transcription inhibitor. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. May have a function in the deetiolation process. Confers sensitivity to abscisic acid (ABA), and regulates the ABA signaling pathway during seed germination, upon nitrate-mediated lateral root inhibition, in hexokinase-dependent sugar responses (including feed-back regulation of photosynthesis and mobilization of storage lipid during germination), and in response to osmotic stress mediated by NaCl, KCl or mannitol. Plays a role in sucrose sensing or signaling, especially at low fluence far red light. Also involved in plant response to glucose treatment, especially at low concentration and in young seedlings. Required for the trehalose-mediated root inhibition and starch accumulation in cotyledons, probably by inhibiting starch breakdown. However, seems to not be involved in sugar-mediated senescence. Required for the ABA-dependent beta-amino-butyric acid (BABA) signaling pathway. BABA primes ABA synthesis and promotes resistance to drought and salt, and leads to a prime callose accumulation that confers resistance against necrotrophic pathogens such as A.brassicicola and P.cucumerina. Seems to be involved in resistance to S.sclerotiorum probably by regulating the ABA-mediated stomatal closure apparently by antagonistic interaction with oxalate. Negative regulator of low water potential-induced Pro accumulation whose effect is decreased by high levels of sugar.