NCBI Accession #
NP_195614.2
NCBI GenBank Nucleotide #
NM_120063.6
NCBI Official Full Name
MATE efflux family protein
NCBI Official Symbol
EDS5
NCBI Official Synonym Symbols
ENHANCED DISEASE SUSCEPTIBILITY 5; F19H22.130; F19H22_130; SALICYLIC ACID INDUCTION DEFICIENT 1; SCORD3; SID1; susceptible to coronatine-deficient Pst DC3000 3
NCBI Protein Information
MATE efflux family protein
NCBI Summary
Encodes an orphan multidrug and toxin extrusion transporter. Essential component of salicylic acid-dependent signaling for disease resistance. Member of the MATE-transporter family. Expression induced by salicylic acid. Mutants are salicylic acid-deficient.
UniProt Synonym Gene Names
Protein SCORD3
UniProt Protein Name
Protein DETOXIFICATION 47, chloroplastic
UniProt Synonym Protein Names
Multidrug and toxic compound extrusion protein 47
UniProt Primary Accession #
Q945F0
UniProt Secondary Accession #
Q67ZP3; Q9SVJ0
UniProt Related Accession #
Q945F0
UniProt Comments
Functions as a multidrug and toxin extrusion transporter in the export of salicylic acid (SA) from the chloroplast to the cytoplasm (PubMed:23757404). Plays an essential function in plant defense via the pathogen-induced salicylic acid (SA) accumulation (PubMed:11826312, PubMed:24594657). Acts also as a key component of the Age-related resistance (ARR) pathway (PubMed:11884688, PubMed:19694953, PubMed:24594657).