Endoplasmic oxidoreductin-2 (AERO2), Recombinant Protein
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Endoplasmic oxidoreductin-2 (AERO2), Recombinant Protein

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Cat: RP04654
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Endoplasmic oxidoreductin-2 (AERO2)
Product Gene Name
AERO2 recombinant protein
Product Synonym Gene Name
AERO2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
VFLNTQNSSI SEFTGKICNC RQAEQQKYIG IVEDCCCDYE TVNRLNTEVL NPLLQDLVKT PFYRYFKVKL WCDCPFWPDD GMCRLRDCSV CECPESEFPE VFKKPLSQYN PVCQEGKPQA TVDRTLDTRA FRGWTVTDNP WTSDDETDND EMTYVNLRLN PERYTGYIGP SARRIWEAIY SENCPKHTSE GSCQEEKILY KLVSGLHSSI SVHIASDYLL DEATNLWGQN LTLLYDRVLR YPDRVQNLYF TFLFVLRAVT KAEDYLGEAE YETGNVIEDL KTKSLVKQVV SDPKTKAACP VPFDEAKLWK GQRGPELKQQ LEKQFRNISA IMDCVGCEKC RLWGKLQILG LGTALKILFT VNGEDNLRHN LELQRNEVIA LMNLLHRLSE SVKYVHDMSP AAERIAGGHA SSGNSFWQRI VTSIAQSKAV SGKRS
Sequence Positions
38-472, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
53,449 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Endoplasmic reticulum oxidoreductin

NCBI/Uniprot Data

NCBI Accession #
NP_181430.2
NCBI GI #
42569753
NCBI GenBank Nucleotide #
NM_129454.4
NCBI GeneID
818481
NCBI Official Full Name
endoplasmic reticulum oxidoreductins 2
NCBI Official Symbol
ERO2
NCBI Official Synonym Symbols
AERO2; endoplasmic reticulum oxidoreductins 2; T7F6.13; T7F6_13
NCBI Protein Information
endoplasmic reticulum oxidoreductins 2
NCBI Summary
endoplasmic reticulum oxidoreductin
UniProt Gene Name
AERO2
UniProt Synonym Gene Names
ERO2
UniProt Protein Name
Endoplasmic reticulum oxidoreductin-2
UniProt Primary Accession #
Q7X9I4
UniProt Secondary Accession #
Q9ZV11
UniProt Related Accession #
Q7X9I4
UniProt Comments
Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on PDI to transfer oxidizing equivalent. Does not oxidize all PDI related proteins, suggesting that it can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress .

For research use only, not for clinical use.