Endoplasmic oxidoreductin-1 (AERO1), Recombinant Protein
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Endoplasmic oxidoreductin-1 (AERO1), Recombinant Protein

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Cat: RP05423
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Endoplasmic oxidoreductin-1 (AERO1)
Product Gene Name
AERO1 recombinant protein
Product Synonym Gene Name
AERO1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
RTNSNVGFFF SDRNSCSCSL QKTGKYKGMI EDCCCDYETV DNLNTEVLNP LLQDLVTTPF FRYYKVKLWC DCPFWPDDGM CRLRDCSVCE CPENEFPEPF KKPFVPGLPS DDLKCQEGKP QGAVDRTIDN RAFRGWVETK NPWTHDDDTD SGEMSYVNLQ LNPERYTGYT GPSARRIWDS IYSENCPKYS SGETCPEKKV LYKLISGLHS SISMHIAADY LLDESRNQWG QNIELMYDRI LRHPDRVRNM YFTYLFVLRA VTKATAYLEQ AEYDTGNHAE DLKTQSLIKQ LLYSPKLQTA CPVPFDEAKL WQGQSGPELK QQIQKQFRNI SALMDCVGCE KCRLWGKLQV QGLGTALKIL FSVGNQDIGD QTLQLQRNEV IALVNLLNRL SESVKMVHDM SPDVERLMED QIAKVSAKPA RLRRIWDLAV SFW
Sequence Positions
37-469, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
53,830 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Endoplasmic reticulum oxidoreductin

NCBI/Uniprot Data

NCBI Accession #
NP_177372.1
NCBI GI #
15218421
NCBI GenBank Nucleotide #
NM_105887.4
NCBI GeneID
843560
NCBI Official Full Name
endoplasmic reticulum oxidoreductins 1
NCBI Official Symbol
ERO1
NCBI Official Synonym Symbols
AERO1; endoplasmic reticulum oxidoreductins 1; T9N14.18; T9N14_18
NCBI Protein Information
endoplasmic reticulum oxidoreductins 1
NCBI Summary
endoplasmic reticulum oxidoreductin
UniProt Gene Name
AERO1
UniProt Synonym Gene Names
ERO1
UniProt Protein Name
Endoplasmic reticulum oxidoreductin-1
UniProt Primary Accession #
Q9C7S7
UniProt Related Accession #
Q9C7S7
UniProt Comments
Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on PDI to transfer oxidizing equivalent. Does not oxidize all PDI related proteins, suggesting that it can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress .

For research use only, not for clinical use.