E3 ubiquitin-protein ligase ORTHRUS 5 (ORTH5), Recombinant Protein
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E3 ubiquitin-protein ligase ORTHRUS 5 (ORTH5), Recombinant Protein

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Cat: RP05547
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana E3 ubiquitin-protein ligase ORTHRUS 5 (ORTH5) , partial
Product Gene Name
ORTH5 recombinant protein
Product Synonym Gene Name
ORTH5
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
68,719 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
E3 ubiquitin-protein ligase

NCBI/Uniprot Data

NCBI Accession #
NP_176779.2
NCBI GI #
42562989
NCBI GenBank Nucleotide #
NM_105276.4
NCBI GeneID
842919
NCBI Official Full Name
Zinc finger (C3HC4-type RING finger) family protein
NCBI Official Symbol
VIM2
NCBI Official Synonym Symbols
F15E12.5; F15E12_5; ORTH5; ORTHRUS 5; VARIANT IN METHYLATION 2
NCBI Protein Information
Zinc finger (C3HC4-type RING finger) family protein
NCBI Summary
Encodes a protein that is similar to VIM1 but is not involved in cytosine methylation. This protein has an N-terminal PHD domain and two RING domains surrounding an SRA domain. ORTH5/VIM2 has E3 ubiquitin ligase activity in vitro.
UniProt Gene Name
ORTH5
UniProt Synonym Gene Names
VIM2
UniProt Protein Name
E3 ubiquitin-protein ligase ORTHRUS 5
UniProt Synonym Protein Names
Protein VARIANT IN METHYLATION 2; RING-type E3 ubiquitin transferase ORTHRUS 5Curated
UniProt Primary Accession #
Q680I0
UniProt Secondary Accession #
Q6NQ90; Q9C8E0
UniProt Related Accession #
Q680I0
UniProt Comments
E3 ubiquitin-protein ligase. Participates in CpG methylation-dependent transcriptional regulation and epigenetic transcriptional silencing. Mediates ubiquitination with the E2 ubiquitin-conjugating enzyme UBC11.

For research use only, not for clinical use.