NCBI Accession #
NP_188133.2
NCBI GenBank Nucleotide #
NM_112378.3
NCBI Official Full Name
RING/U-box superfamily protein
NCBI Official Symbol
HPY2
NCBI Official Synonym Symbols
A. THALIANA METHYL METHANE SULFONATE SENSITIVITY 21; ATMMS21; HIGH PLOIDY2; METHYL METHANE SULFONATE SENSITIVITY 2; MMS21
NCBI Protein Information
RING/U-box superfamily protein
NCBI Summary
Encodes a SUMO E3 ligase that regulates endocycle onset and meristem maintenance.
UniProt Synonym Gene Names
HPY2; AtMMS21
UniProt Protein Name
E3 SUMO-protein ligase MMS21
UniProt Synonym Protein Names
E3 SUMO-protein transferase MMS21Curated; MMS21 homolog; AtMMS21; Protein HIGH PLOIDY 2
UniProt Primary Accession #
Q8GYH7
UniProt Secondary Accession #
Q9LIM0
UniProt Related Accession #
Q8GYH7
UniProt Comments
E3 SUMO-protein ligase that modulates cell cycle progression and functions as a repressor of endocycle onset in meristems. May function downstream of the meristem patterning transcription factors PLETHORA 1 and 2 (PLT1 and PLT2) in root meristem development. Modulates the expression of the mitotic cyclins CYCB1-1 and CYCB1-2 and cyclin-dependent kinases CDKB1-1 and CDKB2-1 in root meristem. Involved in cytokinin signaling in root development.