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Dynamin-related protein 1E (DRP1E), Recombinant Protein
Cat: RP05110
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Dynamin-related protein 1E (DRP1E) , partial
Product Gene Name
DRP1E recombinant protein
Product Synonym Gene Name
DRP1E
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
69,804 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Dynamin-related protein
NCBI/Uniprot Data
NCBI Accession #
NP_567094.1
NCBI GI #
18411520
NCBI GenBank Nucleotide #
NM_115882.4
NCBI GeneID
825189
NCBI Official Full Name
DYNAMIN-like 1E
NCBI Official Symbol
DL1E
NCBI Official Synonym Symbols
ADL1E; ADL4; ADLP2; ARABIDOPSIS DYNAMIN-LIKE 4; DRP1E; DYNAMIN-like 1E; DYNAMIN-LIKE PROTEIN 2; DYNAMIN-RELATED PROTEIN 1E; EDR3; ENHANCED DISEASE RESISTANCE 3; F27H5.4
NCBI Protein Information
DYNAMIN-like 1E
NCBI Summary
At3g60190 encodes Arabidopsis dynamin-related protein 1E, DRP1E, also known as EDR3, ADL4 and ADL1E, which is 624 amino acid residues long, has a predicted mass of 69.8 kDa and a pI of 7.5. Dynamin-related protein 1E belongs to a plant-specific subclass of dynamin-related proteins (DRP1), consisting of five members in Arabidopsis (A, B, C, D, E). This class is characterized by having an N-terminal GTPase domain, a central #Aeodynamin 2#Aeo domain and a C-terminal GTPase effector domain (GED), a typical structure for plant dynamin-related proteins. However, this class lacks a PH domain and a proline-rich domain, which are found in classical animal dynamin-like proteins. Based on work on animal dynamins, the plant DRP1 proteins should be able to form polymeric structures that wrap around membranes to facilitate membrane tubulation and pinching off of vesicles, processes that are essential to vesicle trafficking and membrane compartmentalization. The edr3 mutation causes a P77L substitution in the G2 motif of the GTPase domain of DRP1E. edr3 mutant Arabidopsis plants display enhanced cell death in response to powdery mildew infection.
UniProt Gene Name
DRP1E
UniProt Synonym Gene Names
ADL1E; ADL4; DLP2
UniProt Protein Name
Dynamin-related protein 1E
UniProt Synonym Protein Names
Dynamin-like protein 4; Dynamin-like protein DLP2; Dynamin-like protein E
UniProt Primary Accession #
Q9FNX5
UniProt Secondary Accession #
Q9M1C4; Q9SE82
UniProt Related Accession #
Q9FNX5
UniProt Comments
Microtubule-associated force-producing protein that is targeted to the tubulo-vesicular network of the forming cell plate during cytokinesis. Plays also a major role in plasma membrane maintenance and cell wall integrity with an implication in vesicular trafficking, polar cell expansion, and other aspects of plant growth and development.
For research use only, not for clinical use.