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Dynamin-like protein ARC5 (ARC5), Recombinant Protein
Cat: RP03060
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Dynamin-like protein ARC5 (ARC5) , partial
Product Gene Name
ARC5 recombinant protein
Product Synonym Gene Name
ARC5
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
83,515 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Dynamin-like protein
NCBI/Uniprot Data
NCBI Accession #
NP_188606.2
NCBI GI #
42565028
NCBI GenBank Nucleotide #
NM_112862.4
NCBI GeneID
821509
NCBI Official Full Name
P-loop containing nucleoside triphosphate hydrolases superfamily protein
NCBI Official Symbol
ARC5
NCBI Official Synonym Symbols
ACCUMULATION AND REPLICATION OF CHLOROPLAST 5; DRP5B; Dynamin related protein 5B
NCBI Protein Information
P-loop containing nucleoside triphosphate hydrolases superfamily protein
NCBI Summary
Encodes a novel chloroplast division protein. Mutants of exhibit defects in chloroplast constriction, have enlarged, dumbbell-shaped chloroplasts. The ARC5 gene product shares similarity with the dynamin family of GTPases, which mediate endocytosis, mitochondrial division, and other organellar fission and fusion events in eukaryotes. Phylogenetic analysis showed that ARC5 is related to a group of dynamin-like proteins unique to plants. A GFP-ARC5 fusion protein localizes to a ring at the chloroplast division site. Chloroplast import and protease protection assays indicate that the ARC5 ring is positioned on the outer surface of the chloroplast. Facilitates separation of the two daughter chloroplasts.
UniProt Gene Name
ARC5
UniProt Synonym Gene Names
DRP5B
UniProt Protein Name
Dynamin-like protein ARC5
UniProt Synonym Protein Names
Dynamin-related protein 5B; Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 5
UniProt Primary Accession #
Q84N64
UniProt Secondary Accession #
Q3EB39; Q9LJM3
UniProt Related Accession #
Q84N64
UniProt Comments
Probable GTPase component of both plastid and peroxisme division machinery. Required for the last steps of plastid division specifically in mesophyll-cell, when the narrow isthmus breaks, facilitating the separation of the daughter plastids. Necessary for peroxisome activities. Seems to influence stromule (stroma-filled tubular extensions of the plastid envelope membrane) length and frequency.
For research use only, not for clinical use.