NCBI Accession #
NP_001189821.1
NCBI GenBank Nucleotide #
NM_001202892.1
NCBI Official Full Name
MAPK phosphatase 2
NCBI Official Symbol
MKP2
NCBI Official Synonym Symbols
ARABIDOPSIS MAPK PHOSPHATASE 2; ATMKP2; DSPTP1B; DUAL-SPECIFICITY PROTEIN PHOSPHATASE 1B; F28L1.5; F28L1_5; MAPK phosphatase 2
NCBI Protein Information
MAPK phosphatase 2
NCBI Summary
Encodes a nuclear-localized MAP kinase phosphatase. Plants with reduced levels of MKP2 transcripts are hypersensitive to ozone and ozone-mediated activation of MPK3 and MPK6 is prolonged in these plants.
UniProt Gene Name
DSPTP1B
UniProt Synonym Gene Names
MKP2; AtDsPTP1B; AtMKP2
UniProt Protein Name
Dual specificity protein phosphatase 1B
UniProt Synonym Protein Names
MAPK phosphatase 2; AtMKP2
UniProt Primary Accession #
Q9M8K7
UniProt Secondary Accession #
Q8LDW2
UniProt Related Accession #
Q9M8K7
UniProt Comments
Has a dual specificity toward Ser/Thr and Tyr-containing proteins. Prevents biotic and abiotic stress responses, including ozone, oxidative stress and pathogen attacks; represses MAPK activities during hypersensitive response to limit the spread of the HR response after infection by necrotrophic pathogen such as Botrytis cinerea. May be also involved in ABA and salt responses. Dephosphorylates MPK3 and MPK6.