NCBI Accession #
NP_188714.2
NCBI GenBank Nucleotide #
NM_112969.3
NCBI Official Full Name
topoisomerase 6 subunit B
NCBI Official Symbol
TOP6B
NCBI Official Synonym Symbols
ATTOP6B; BIN3; BRASSINOSTEROID INSENSITIVE 3; ELONGATED HYPOCOTYL 6; HARLEQUIN; HLQ; HYP6; RHL3; ROOT HAIRLESS 3; topoisomerase 6 subunit B; topoisomerase 6 subunit B
NCBI Protein Information
topoisomerase 6 subunit B
NCBI Summary
Encodes putative eukaryotic homolog of archaebacterial topoisomerase VI subunit B, TOP6B. Is essential for endoreduplication and is involved in cell expansion and cell proliferation. The hlq (harlequin) dwarf mutant has fewer root hair and leaf trichome. It has abnormal epidermal cell and accumulates callose.
UniProt Synonym Gene Names
AtTOP6B
UniProt Protein Name
DNA topoisomerase 6 subunit B
UniProt Synonym Protein Names
Protein BRASSINOSTEROID INSENSITIVE 3; Protein ELONGATED HYPOCOTYL 6; Protein ROOT HAIRLESS 3
UniProt Primary Accession #
Q9C5V6
UniProt Secondary Accession #
Q9LT43
UniProt Related Accession #
Q9C5V6
UniProt Comments
Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP. Involved in cell-elongation processes.