NCBI Accession #
NP_001154639.1
NCBI GenBank Nucleotide #
NM_001161167.1
NCBI Official Full Name
DNA ligase IV-binding protein
NCBI Official Symbol
XRCC4
NCBI Official Synonym Symbols
homolog of human DNA ligase iv-binding protein XRCC4; homolog of X-ray repair cross complementing 4
NCBI Protein Information
DNA ligase IV-binding protein
NCBI Summary
A. thaliana homologue of the human DNA ligase IV-binding protein XRCC4. Yeast two-hybrid analysis demonstrated a strong interaction between A. thaliana DNA ligase IV and the A. thaliana homologue of the human DNA ligase IV-binding protein XRCC4. This interaction is shown to be mediated via the tandem BRCA C-terminal domains of A. thaliana DNA ligase IV protein.
UniProt Protein Name
DNA repair protein XRCC4
UniProt Primary Accession #
Q682V0
UniProt Secondary Accession #
Q9LS81
UniProt Related Accession #
Q682V0
UniProt Comments
May be involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair. May bind to DNA. The LIG4-XRCC4 complex is probably responsible for the NHEJ ligation step, and XRCC4 may enhance the joining activity of LIG4 .