DNA repair endonuclease UVH1 (UVH1), Recombinant Protein
  1. Home
  2. Products
  3. Plant Proteins
  4. Recombinant Plant Proteins
  5. Recombinant Arabidopsis Thaliana Protein
Products
Online Inquiry

DNA repair endonuclease UVH1 (UVH1), Recombinant Protein

Inquiry
Cat: RP03018
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana DNA repair endonuclease UVH1 (UVH1) , partial
Product Gene Name
UVH1 recombinant protein
Product Synonym Gene Name
UVH1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
87,975 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
DNA repair endonuclease

NCBI/Uniprot Data

NCBI Accession #
NP_198931.1
NCBI GI #
15237571
NCBI GenBank Nucleotide #
NM_123480.4
NCBI GeneID
834117
NCBI Official Full Name
Restriction endonuclease, type II-like superfamily protein
NCBI Official Symbol
UVH1
NCBI Official Synonym Symbols
ATRAD1; MEE6.22; MEE6_22; RAD1; REPAIR ENDONUCLEASE; ULTRAVIOLET HYPERSENSITIVE 1
NCBI Protein Information
Restriction endonuclease, type II-like superfamily protein
NCBI Summary
Confers resistance to UV radiation. Homolog of the human xeroderma pigmentosum group F DNA repair and yeast Rad1 proteins
UniProt Gene Name
UVH1
UniProt Synonym Gene Names
RAD1; AtRAD1
UniProt Protein Name
DNA repair endonuclease UVH1
UniProt Synonym Protein Names
DNA excision repair protein XP-F homolog; Ultraviolet hypersensitive 1; AtRAD1
UniProt Primary Accession #
Q9LKI5
UniProt Secondary Accession #
Q9SE36; Q9SPL7
UniProt Related Accession #
Q9LKI5
UniProt Comments
Seems to be involved in nucleotide excision repair (NER) of damaged DNA (dark repair mechanism). Involved in repair of UV light, and probably oxidative damage. The UVH1/RAD1-ERCC1/RAD10 complex may act as an endonuclease making DNA incision 5' to the lesion site. In vitro, is implicated in double strand breaks (DSBs) repair and is required for homologous recombination in the presence of non-homologous overhangs. May mediate the induction of a DNA-damage sensitive cell-cycle checkpoint during the G2 phase.

For research use only, not for clinical use.