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DNA polymerase alpha catalytic subunit (POLA), Recombinant Protein
Cat: RP02834
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana DNA polymerase alpha catalytic subunit (POLA) , partial
Product Gene Name
POLA recombinant protein
Product Synonym Gene Name
POLA
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
170,479 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
DNA polymerase
NCBI/Uniprot Data
NCBI Accession #
NP_001331725.1
NCBI GI #
1063743798
NCBI GenBank Nucleotide #
NM_001345811.1
NCBI GeneID
836845
NCBI Official Full Name
DNA-directed DNA polymerase
NCBI Official Symbol
ICU2
NCBI Official Synonym Symbols
INCURVATA2; K21H1.14; K21H1_14
NCBI Protein Information
DNA-directed DNA polymerase
NCBI Summary
Encodes the putative catalytic subunit of the DNA polymerase alpha. Interacts with genes involved in chromatin-mediated cellular memory. ICU2 genetically interacts with TERMINAL FLOWER2, the ortholog of HETEROCHROMATIN PROTEIN1 of animals and yeasts, and with the Polycomb group (PcG) gene CURLY LEAF. A number of regulatory genes were derepressed in the icu2-1 mutant, including genes associated with flowering time, floral meristem, and floral organ identity. Mutant has curled, involute leaves and causes early flowering.
UniProt Gene Name
POLA
UniProt Protein Name
DNA polymerase alpha catalytic subunit
UniProt Primary Accession #
Q9FHA3
UniProt Secondary Accession #
F4K285
UniProt Related Accession #
Q9FHA3
UniProt Comments
Polymerase alpha in a complex with DNA primase is a replicative polymerase.
For research use only, not for clinical use.