DNA mismatch repair protein Msh6-2 (MSH6-2), Recombinant Protein
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DNA mismatch repair protein Msh6-2 (MSH6-2), Recombinant Protein

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Cat: RP07151
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana DNA mismatch repair protein Msh6-2 (MSH6-2) , partial
Product Gene Name
MSH6-2 recombinant protein
Product Synonym Gene Name
MSH6-2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
122,270 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_850630.1
NCBI GI #
30687514
NCBI GenBank Nucleotide #
NM_180299.1
NCBI GeneID
822040
NCBI Official Full Name
MUTS homolog 7
NCBI Official Symbol
MSH7
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA MUTS HOMOLOG 7; ATMSH7; MSH6-2; MUTS HOMOLOG 6-2; MUTS homolog 7
NCBI Protein Information
MUTS homolog 7
NCBI Summary
encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH7 exhibit moderate affinity for a (T/G) substrate and weak binding of (+T), suggesting MSH2*MSH7 may be specialized for lesions/base mispairs not tested or for (T/G) mispairs in special contexts.
UniProt Gene Name
MSH7
UniProt Synonym Gene Names
MSH6-2; AtMSH7
UniProt Protein Name
DNA mismatch repair protein MSH7
UniProt Synonym Protein Names
MutS protein homolog 7
UniProt Primary Accession #
Q9SMV7
UniProt Secondary Accession #
O22372; Q9SNZ4
UniProt Related Accession #
Q9SMV7
UniProt Comments
Component of the post-replicative DNA mismatch repair system (MMR). Forms the heterodimer MutS gamma (MSH2-MSH7 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. MutS gamma recognizes specifically the T/G single base mismatch, but not trinucleotide insertion-deletion loops (IDL).

For research use only, not for clinical use.