DNA mismatch repair protein Msh6-1 (MSH6-1), Recombinant Protein
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DNA mismatch repair protein Msh6-1 (MSH6-1), Recombinant Protein

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Cat: RP06712
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana DNA mismatch repair protein Msh6-1 (MSH6-1) , partial
Product Gene Name
MSH6-1 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
ALENLEIFEN SRNGGYSGTL YAQLNQCITA SGKRLLKTWL ARPLYNTELI KERQDAVAIL RGENLPYSLE FRKSLSRLPD MERLIARMFS SIEASGRNGD KVVLYEDTAK KQVQEFISTL RGCETMAEAC SSLRAILKHD TSRRLLHLLT PGQSLPNISS SIKYFKDAFD WVEAHNSGRV IPHEGADEEY DCACKTVEEF ESSLKKHLKE QRKLLGDASI NYVTVGKDEY LLEVPESLSG SVPHDYELCS SKKGVSRYWT PTIKKLLKEL SQAKSEKESA LKSISQRLIG RFCEHQEKWR QLVSATAELD VLISLAFASD SYEGVRCRPV ISGSTSDGVP HLSATGLGHP VLRGD
Sequence Positions
702-1056aa; Partial
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
146,797 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_192116.1
NCBI GI #
15235223
NCBI GenBank Nucleotide #
NM_116438.2
NCBI GeneID
828147
NCBI Official Full Name
MUTS homolog 6
NCBI Official Symbol
MSH6
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA MUTS HOMOLOG 6; ATMSH6; MSH6-1; MUTS HOMOLOG 6-1; MUTS homolog 6; MUTS HOMOLOG 6-1; T10M13.8; T10M13_8
NCBI Protein Information
MUTS homolog 6
NCBI Summary
encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH6 bound the (+T) substrate strongly, (T/G) well, and (+AAG) no better than it did a (T/A) homoduplex.
UniProt Gene Name
MSH6
UniProt Synonym Gene Names
AGAA.3; MSH6-1; AtMSH6
UniProt Protein Name
DNA mismatch repair protein MSH6
UniProt Synonym Protein Names
MutS protein homolog 6
UniProt Primary Accession #
O04716
UniProt Related Accession #
O04716
UniProt Comments
Component of the post-replicative DNA mismatch repair system (MMR). Forms the heterodimer MutS alpha (MSH2-MSH6 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. MutS alpha recognizes single base mismatches and trinucleotide insertion-deletion loops (IDL) in the DNA. Is involved in a UV-B-induced DNA damage response pathway.

For research use only, not for clinical use.