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DNA ligase 4 (LIG4), Recombinant Protein
Cat: RP02921
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana DNA ligase 4 (LIG4) , partial
Product Gene Name
LIG4 recombinant protein
Product Synonym Gene Name
LIG4
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
137,851 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
DNA ligase
NCBI/Uniprot Data
NCBI Accession #
NP_568851.2
NCBI GI #
30696835
NCBI GenBank Nucleotide #
NM_125098.4
NCBI GeneID
835822
NCBI Official Full Name
DNA ligase IV
NCBI Official Symbol
ATLIG4
NCBI Official Synonym Symbols
DNA LIGASE IV; LIG4
NCBI Protein Information
DNA ligase IV
NCBI Summary
Encodes the Arabidopsis orthologue of the yeast and mammalian DNA ligase IV. Involved in the repair of DNA damage but, unlike in yeast, not required for T-DNA integration. Interacts with the Arabidopsis homologue of XRCC4.
UniProt Gene Name
LIG4
UniProt Protein Name
DNA ligase 4
UniProt Synonym Protein Names
DNA ligase IV; Polydeoxyribonucleotide synthase [ATP] 4
UniProt Primary Accession #
Q9LL84
UniProt Secondary Accession #
Q9LU70
UniProt Related Accession #
Q9LL84
UniProt Comments
Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair. May be involved for T-DNA integration even if not absolutely required. Seems to be dispensable under normal growth conditions.
For research use only, not for clinical use.