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DNA helicase INO80 (INO80), Recombinant Protein
Cat: RP05857
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana DNA helicase INO80 (INO80) , partial
Product Gene Name
INO80 recombinant protein
Product Synonym Gene Name
INO80
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
172,172 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
DNA helicase
NCBI/Uniprot Data
NCBI Accession #
NP_001319776.1
NCBI GI #
1063717329
NCBI GenBank Nucleotide #
NM_001339850.1
NCBI GeneID
824897
NCBI Official Full Name
DNA helicase INO80-like protein
NCBI Official Symbol
INO80
NCBI Official Synonym Symbols
ATINO80; INO80 ortholog; INO80 ORTHOLOG
NCBI Protein Information
DNA helicase INO80-like protein
NCBI Summary
Encodes the Arabidopsis INO80 ortholog of the SWI/SNF ATPase family. Functions as a positive regulator of DNA homologous recombination (HR). In INO80 mutants, the HR frequency is reduced to 15% of that in the wild-type. Mutation in INO80 does not affect sensitivity to genotoxic agents and efficiency of T-DNA integration. INO80 was also shown to regulate a subset of the Arabidopsis transcriptome.
UniProt Gene Name
INO80
UniProt Synonym Gene Names
AtINO80
UniProt Protein Name
DNA helicase INO80
UniProt Synonym Protein Names
Putative DNA helicase INO80 complex homolog 1
UniProt Primary Accession #
Q8RXS6
UniProt Secondary Accession #
Q9M2L7
UniProt Related Accession #
Q8RXS6
UniProt Comments
DNA helicase and probable main scaffold component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. Positive regulator of homologous recombination, but not an essential component of homologous recombination. Not involved in the illegitimate repair pathway.
For research use only, not for clinical use.