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DNA-directed RNA polymerase II subunit RPB2 (RPB135), Recombinant Protein
Cat: RP06870
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana DNA-directed RNA polymerase II subunit RPB2 (RPB135) , partial
Product Gene Name
RPB135 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
135,019 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
NCBI/Uniprot Data
NCBI Accession #
NP_193902.1
NCBI GI #
15234572
NCBI GenBank Nucleotide #
NM_118291.4
NCBI GeneID
828259
NCBI Official Full Name
DNA-directed RNA polymerase family protein
NCBI Official Symbol
NRPB2
NCBI Official Synonym Symbols
EMB1989; EMBRYO DEFECTIVE 1989; F17L22.170; F17L22_170; RPB2
NCBI Protein Information
DNA-directed RNA polymerase family protein
NCBI Summary
Encodes the unique second-largest subunit of DNA-dependent RNA polymerase II; the ortholog of budding yeast RPB2 and a homolog of the E. coli RNA polymerase beta subunit.
UniProt Gene Name
NRPB2
UniProt Synonym Gene Names
EMB1989; RP140; RPB135; RPB2; RNA polymerase II subunit 2; RNA polymerase II subunit B2
UniProt Protein Name
DNA-directed RNA polymerase II subunit 2
UniProt Synonym Protein Names
DNA-directed RNA polymerase II 135 kDa polypeptide; DNA-directed RNA polymerase II subunit RPB2 (EC:2.7.7.6); RNA polymerase II subunit 2; RNA polymerase II subunit B2; Protein EMBRYO DEFECTIVE 1989
UniProt Primary Accession #
P38420
UniProt Secondary Accession #
Q9SVS6
UniProt Related Accession #
P38420
UniProt Comments
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. NRPB2 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template .
For research use only, not for clinical use.