NCBI Accession #
NP_190777.1
NCBI GenBank Nucleotide #
NM_115068.5
NCBI Official Full Name
DNA-directed RNA polymerase, RBP11-like protein
NCBI Official Symbol
NRPB11
NCBI Official Synonym Symbols
ATRPB13.6; NRPD11; NRPE11; RNA POLYMERASE II 13.6 KDA SUBUNIT
NCBI Protein Information
DNA-directed RNA polymerase, RBP11-like protein
NCBI Summary
Non-catalytic subunit common to nuclear DNA-dependent RNA polymerases II, IV and V; homologous to budding yeast RPB11 and the E. oli RNA polymerase alpha subunit.
UniProt Synonym Gene Names
NRPD11; NRPE11; RPB13.6; RNA polymerase II subunit B11
UniProt Protein Name
DNA-directed RNA polymerases II, IV and V subunit 11
UniProt Synonym Protein Names
DNA-directed RNA polymerase II 13.6 kDa polypeptide; DNA-directed RNA polymerase II subunit J; DNA-directed RNA polymerase II subunit RPB11; RNA polymerase II subunit B11
UniProt Primary Accession #
Q38859
UniProt Related Accession #
Q38859
UniProt Comments
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. NRPB11 is part of the core element with the central large cleft. Component of RNA polymerases IV and V which mediate short-interfering RNAs (siRNA) accumulation and subsequent RNA-directed DNA methylation-dependent (RdDM) transcriptional gene silencing (TGS) of endogenous repeated sequences, including transposable elements.