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DNA-directed RNA polymerase D subunit 2b (NRPD2b), Recombinant Protein
Cat: RP07125
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana DNA-directed RNA polymerase D subunit 2b (NRPD2b) , partial
Product Gene Name
NRPD2b recombinant protein
Product Synonym Gene Name
NRPD2b
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
118,968 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
DNA-directed RNA polymerase
NCBI/Uniprot Data
NCBI Accession #
NP_188437.2
NCBI GI #
145338664
NCBI GenBank Nucleotide #
NM_112691.4
NCBI GeneID
821334
NCBI Official Full Name
nuclear RNA polymerase D2B
NCBI Official Symbol
NRPD2B
NCBI Official Synonym Symbols
nuclear RNA polymerase D2B
NCBI Protein Information
nuclear RNA polymerase D2B
NCBI Summary
Encodes a subunit of RNA polymerase IV (aka RNA polymerase D). NRPD2b is closely related to NRPD2a, but has lower levels of transcription and does not affect endogenous siRNA when mutated.
UniProt Gene Name
NRPD2b
UniProt Synonym Gene Names
RPD2b; AtNRPD2b; Nuclear RNA polymerase D 2b; POL IV 2b
UniProt Protein Name
DNA-directed RNA polymerase D subunit 2b
UniProt Synonym Protein Names
RNA polymerase IV subunit 2b; POL IV 2b
UniProt Primary Accession #
Q9LV32
UniProt Secondary Accession #
Q1ANE6
UniProt Comments
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase IVa and IVb which mediate short-interfering RNAs (siRNA) accumulation and subsequent RNA-directed DNA methylation-dependent (RdDM) silencing of endogenous repeated sequences, including transposable largest subunit. Also required for full erasure of methylation elements. Required for intercellular RNA interference (RNAi) leading to systemic post-transcriptional gene silencing (Probable).
For research use only, not for clinical use.