DNA-binding protein BIN4 (BIN4), Recombinant Protein
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DNA-binding protein BIN4 (BIN4), Recombinant Protein

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Cat: RP03195
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana DNA-binding protein BIN4 (BIN4)
Product Gene Name
BIN4 recombinant protein
Product Synonym Gene Name
BIN4
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MSSSSREGSP DWLRSYEAPM TTSLLSLSSS DDDSPYRESE VISSLPLPDD DGDDIVVLET ESVELLTRKN SETKVVTKQV SIEQVFSRKK KADASLNLED SCAGKENGNN VDCEKLSSKH KDAQGGADSV WLVSSDSEPS SPIKQEVTVS TEKDADFVLE ATEEEPAVKT VRKEKSPKTK SKSSRKTPKE GNSAQEILKT EDKDTDTTIA EQVTPEKSPK TKSKSSRKTP KEENCAQEIL KTEDKDKDTD TDTIIAEEVT TDQKIKPSSG SSSRLPLVLS EKVNRTKVLV ECEGDSIDLS GDMGAVGRVV VSDTTGDMYL DLKGTIYKST IIPSRTFCVV NVGQTEAKIE AIMNDFIQLI PQSNVYEAET MVEGTLEGFT FESDDESNKN AKTAVKPADQ SVGTEEETNT KAKPKAKAKG ETVIGKKRGR PSKEKQPPAK KARNSAPKKP KAKK
Sequence Positions
1-454, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
49,485 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
DNA-binding protein

NCBI/Uniprot Data

NCBI Accession #
NP_001154739.1
NCBI GI #
238481373
NCBI GenBank Nucleotide #
NM_001161267.1
NCBI GeneID
832534
NCBI Official Full Name
double-stranded DNA binding protein
NCBI Official Symbol
BIN4
NCBI Official Synonym Symbols
brassinosteroid-insensitive4; K18P6.17; K18P6_17; MID; MIDGET
NCBI Protein Information
double-stranded DNA binding protein
NCBI Summary
This gene is predicted to encode a protein that forms part of the topoisomerase VI complex. BIN4 is a nuclear-localized protein that can bind DNA. bin4 mutants are brassinolide-insensitive dwarves with severely reduced cell size in leaves, roots, and hypocotyls. Proper development of root hairs and trichomes is also disrupted in bin4 mutants and they have elevated levels of double strand breaks in their cotyledon cells.
UniProt Gene Name
BIN4
UniProt Synonym Gene Names
MID
UniProt Protein Name
DNA-binding protein BIN4
UniProt Synonym Protein Names
Protein BRASSINOSTEROID INSENSITIVE 4; Protein MIDGET
UniProt Primary Accession #
Q9FLU1
UniProt Related Accession #
Q9FLU1
UniProt Comments
Component of the DNA topoisomerase VI complex. Binds to DNA. Required for chromatin organization and progression of endoreduplication cycles. The loss of BIN4 activates the ATM- and ATR-dependent DNA damage responses in postmitotic cells and induces the ectopic expression of the mitotic G2/M-specific cyclin B1;1 gene in non-dividing cells.

For research use only, not for clinical use.